ABOUT REGENERATIVE MEDICINE
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Tissue Engineering and Regenerative Medicine
NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING
A comprehensive review of the how and what of regenerative medicine conducted by NIH-funded researchers. Read
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A Systematic Review of Dextrose Prolotherapy for Chronic Musculoskeletal Pain
ORTHOPEDIC REVIEWS
The aim of this study was to systematically review dextrose (d-glucose) prolotherapy efficacy in the treatment of chronic musculoskeletal pain. Read
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A Systematic Review of Four Injection Therapies for Lateral Epicondylosis: Prolotherapy, Polidocanol, Whole Blood and Platelet Rich Plasma
BRITISH JOURNAL OF SPORTS MEDICINE
The aim of this study was to appraise existing evidence for prolotherapy, polidocanol, autologous whole blood and platelet-rich plasma injection therapies for lateral epicondylosis (LE) Read
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A Comprehensive Update of Prolotherapy in the Management of Osteoarthritis of the Knee
ORTHOPEDIC REVIEWS
This is a comprehensive review of the literature focusing on the use of prolotherapy in the treatment of osteoarthritis of the knee. It covers the background, efficacy, and advantages of prolotherapy in the management of osteoarthritis symptoms and then covers the existing evidence of the use of prolotherapy for this purpose. Read
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History of Regenerative Medicine in the Field of Orthopedics
JOURNAL OF ARTHROSCOPIC SURGERY AND SPORTS MEDICINE
The demand and surge of regenerative medical treatments for various musculoskeletal disorders and injuries have increased exponentially in the recent past. We have reviewed the evolution of these treatments, from the past to the present times. Read
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Regenerative Medicine: Current Therapies and Future Directions
PNAS
Organ and tissue loss through disease and injury motivate the development of therapies that can regenerate tissues and decrease reliance on transplantations. Regenerative medicine, an interdisciplinary field that applies engineering and life science principles to promote regeneration, can potentially restore diseased and injured tissues and whole organs. Read
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The platelet-rich plasma and mesenchymal stem cell milieu: A review of therapeutic effects on bone healing
JOURNAL OF ORTHOPAEDIC RESEARCH
Platelet-rich plasma is autologous plasma that contains concentrated platelets compared to whole blood. It is relatively inexpensive to produce, can be easily isolated from whole blood, and can be administered while the patient is in the operating room. Further, because platelet-rich plasma is an autologous therapy, there is minimal risk for adverse reactions to the patient. Read
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Advances and Promises of Nutritional Influences on Natural Bone Repair
JOURNAL OF ORTHOPAEDIC RESEARCH
Of the many possible approaches, nutrition represents a safe, affordable, and non-invasive strategy to positively influence each phase of fracture repair. Read